Collaborators
JC 10 March 2010
This weeks paper is A state-mutating genetic algorithm to design ion-channel models.
Collaborators
Collaborators are an important part of our research program and we are fortunate to have productive interactions with people here in Australia and across the world. Where possible we have linked to their home or institute pages.
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Ectopic firing in DRG neurons
In neuropathic pain, dorsal root ganglion (DRG) neurons generate inappropriate action potentials in the cell body [1]. It is likely that this is due to altered expression of one or more sodium channel subunits [2]. This toy is an implmentation of a published DRG model [2] with the addition of a NaV1.9 [3] and can explore the interaction between the different sodium channel subtypes.
The model is implemented in Matlab. Download source code, windows executable with runtime (170Mb, required first time) or windows executable without runtime (when updating).
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